TNF-alpha inhibitors

Ventricular septal defect

R analysis
id Study   Lib. in paper Exposition period    Study type  Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S3194
R5169
Bröms a (Controls unexposed, disease free), 2016 VSD only 3 months or more before pregnancy or1st trimester population based cohort retrospective unexposed, disease free excluded Adjustment: No 2.66 [1.38;5.14] C
excluded (control group)
9/683   6,238/1,250,192 6,247 683
ref
S3193
R5147
Bröms a (Controls unexposed, sick), 2016 VSD only 3 months or more before pregnancy or1st trimester excluded population based cohort retrospective unexposed, sick Adjustment: No 2.36 [1.20;4.67] C
excluded (exposition period)
9/683   121/21,549 130 683
ref
Total 0 studies NaN [NaN;NaN] 0 0
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

Sensitivity analysis