TNF-alpha inhibitors

Neonatal medical care

R analysis
id Study   Lib. in paper Exposition period    Study type  Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S3066
R4668
Chaparro, 2018 Intensive care unit admission 3 months (or more) before pregnancy or during pregnancy excluded retrospective cohort unexposed, sick Adjustment: No 2.35 [1.21;4.54] C
excluded (exposition period)
27/388   14/453 41 388
ref
S4103
R8790
Lichtenstein - infliximab, 2018 Infants prolonged hospitalization 3 months (or more) before pregnancy or during pregnancy excluded prospective cohort exposed to other treatment, sick Adjustment: No 0.38 [0.13;1.14] C
excluded (exposition period)
5/81   12/82 17 81
ref
S3037
R4573
Seirafi, 2014 Respiratory distress syndrome 3 months (or more) before pregnancy or during pregnancy excluded retrospective cohort unexposed, sick Adjustment: No before conception and/or during pregnancy 1.28 [0.30;5.52] C
excluded (exposition period)
5/118   3/90 8 118
ref
Total 0 studies NaN [NaN;NaN] 0 0
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

Sensitivity analysis