Adalimumab

Caesarean

R analysis
id Study   Lib. in paper Exposition period    Study type  Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S4893
R12916
Broms (Controls exposed to other treatments), 2020 Caesarean section 3 months (or more) before pregnancy or during pregnancy population based cohort retrospective exposed to other treatment, sick excluded Adjustment: No 1.79 [1.39;2.30] C
excluded (control group)
103/257   2,560/9,393 2,663 257
ref
S4892
R12911
Broms (Controls unexposed, disease free), 2020 Caesarean section 3 months (or more) before pregnancy or during pregnancy excluded population based cohort retrospective unexposed, disease free Adjustment: No 3.19 [2.48;4.09] C
excluded (exposition period)
103/257   281,654/1,623,483 281,757 257
ref
S5066
R13190
De Lorenzo (Controls unexposed, disease free), 2020 Caesarean at least 1st trimester retrospective cohort unexposed, disease free excluded Adjustment: No 0.93 [0.03;24.84] C
excluded (control group)
0/2   9/36 9 2
ref
S5067
R13196
De Lorenzo (Controls unexposed, sick), 2020 Caesarean at least 1st trimester excluded retrospective cohort unexposed, sick Adjustment: No 0.46 [0.02;12.10] C
excluded (exposition period)
0/2   13/32 13 2
ref
S5069
R13215
Chambers (Controls unexposed, disease free), 2019 Delivery by Caesarian Section at least 1st trimester prospective cohort unexposed, disease free excluded Adjustment: No 2.34 [1.56;3.51] C
excluded (control group)
107/220   57/198 164 220
ref
S5068
R13200
Chambers (Controls, sick), 2019 Delivery by Caesarian Section at least 1st trimester excluded prospective cohort unexposed, sick Adjustment: No 1.33 [0.84;2.13] C
excluded (exposition period)
107/220   44/106 151 220
ref
Total 0 studies NaN [NaN;NaN] 0 0
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

Sensitivity analysis