Centrally acting antiadrenergic (versus unexposed) - Medication and Pregnancy KB

Centrally acting antiadrenergic (versus unexposed) updated on 03-11-2025

Elective/induced termination of pregnancy

R analysis

id	Study	Lib. in paper	Exposition period	Study type All studies Case control excluded Only case control	Control type	Tags	OR 95%CI	x1/n1 x0/n0	no cases	no exposed	ROB	Ref.
S13390 R51879	Hoeltzenbein - Methyldopa (Controls unexposed, disease free), 2017	Elective termination of pregnancy	at least 1st trimester	prospective cohort	unexposed, disease free	Adjustment: Yes Indications Antihypertensive: All hypertensions, any indications or not specified	0.35 [0.10;1.70]	2/261 20/526	22	261		ref
					Total	1 studies	0.35 [0.08;1.44]		22	261
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; ^C: calculated odds ratio from numbers of events and effectives

Forest plot

1: Controls unexposed, disease free;

Sensitivity analysis

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded