Metoclopramide

Small for gestational age (weight)

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S2397
R3006		 Pasternak, 2013 Small for gestational age (gestational age-birth weight < 10th percentile) during pregnancy (anytime or not specified) population based cohort retrospective unexposed (general population or NOS) Adjustment: Yes 1.00 [0.96;1.04] 3,697/36,864   14,452/147,016 18,149 36,864
ref
S2751
R3658		 Asker, 2005 Small-for-gestational age (< 2 standard deviations from expected weight) during pregnancy (anytime or not specified) population based cohort retrospective unexposed (general population or NOS) Adjustment: Yes 0.65 [0.38;1.09] 14/1,166   14,247/665,572 14,261 1,166
ref
Total 2 studies 0.88 [0.59;1.29] 32,410 38,030
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Pasternak, 2013Pasternak, 2013 1.00[0.96; 1.04]18,14936,86469%ROB confusion: NAROB selection: NAROB classification: NAROB missing: NAROB mesure: NAROB reporting: NA Asker, 2005Asker, 2005 0.65[0.38; 1.09]14,2611,16631%ROB confusion: NAROB selection: NAROB classification: NAROB missing: NAROB mesure: NAROB reporting: NA Total (2 studies) I2 = 61% 0.88[0.59; 1.29]32,41038,0300.22.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 0.88[0.59; 1.29]32,41038,03061%NAPasternak, 2013 Asker, 2005 2 case control studiescase control studies 0 Type of controls unexposed (disease free or unspecified)unexposed (disease free or unspecified) 0.88[0.59; 1.29]32,41038,03061%NAPasternak, 2013 Asker, 2005 2 Tags Adjustment   - Yes  - Yes 0.88[0.59; 1.29]32,41038,03061%NAPasternak, 2013 Asker, 2005 2 All studiesAll studies 0.88[0.59; 1.29]32,41038,03061%NAPasternak, 2013 Asker, 2005 20.210.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) 0.88[0.59; 1.29]32,41038,03061%NAPasternak, 2013 Asker, 2005 20.510.01.0