Misoprostol

Vascular disruption anomalie

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S2836
R3808		 Vargas, 2000 All vascular disruption 1st trimester case control Matched 22.00 [7.30;81.30] 32/44   61/328 93 44
ref
Total 1 studies 22.00 [6.59;73.42] 93 44
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Vargas, 2000Vargas, 2000 22.00[7.30; 81.30]93440%ROB confusion: NAROB selection: NAROB classification: NAROB missing: NAROB mesure: NAROB reporting: NA0.950.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 0 case control studiescase control studies 22.00[6.59; 73.42]9344 -NAVargas, 2000 1 Type of controls Tags MatchedMatched 22.00[6.59; 73.42]9344 -NAVargas, 2000 1 All studiesAll studies 22.00[6.59; 73.42]9344 -NAVargas, 2000 10.550.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls 0.510.01.0