Fluoxetine updated on 07-01-2025

Large head circumference for gestational age

R analysis
id Study   Lib. in paper Exposition period    Study type 
 Control type 
 
Tags OR 95%CI x1/n1 x0/n0 no cases no exposed ROB Ref.
S7693
R22811		 Kivistö, 2016 Head circumference >90th centile (in newborns) during pregnancy (anytime or not specified) retrospective cohort unexposed (general population or NOS) Adjustment: Yes Monotherapy: substance alone among all Antidep (SSRI, SNRI, ...) 0.97 [0.38;2.52] -/-   2,569/- - -
ref
Total 1 studies 0.97 [0.38;2.50] 0 0
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives

Forest plot

StudyTE95% CIn casesn exposedweightROBABCDEF Kivistö, 2016Kivistö, 2016 0.97[0.38; 2.52]--0%ROB confusion: seriousROB selection: criticalROB classification: moderateROB missing: criticalROB mesure: moderateROB reporting: moderate0.22.01.0ROB: A: confusion, B: selection, C: classification, D: missing, E: measurement, F: reportinglow,moderate,serious,critical,unclear,

Sensitivity analysis

SubsetTE95% CIn casesn exposedkI2 Type of studies cohort studiescohort studies 0.97[0.38; 2.50]-- -NAKivistö, 2016 1 case control studiescase control studies 0 Type of controls unexposed (disease free or unspecified)unexposed (disease free or unspecified) 0.97[0.38; 2.50]-- -NAKivistö, 2016 1 Tags Adjustment   - Yes  - Yes 0.97[0.38; 2.50]-- -NAKivistö, 2016 1 Monotherapy   - substance alone among all Antidep ( ...  - substance alone among all Antidep (SSRI, SNRI, ...) 0.97[0.38; 2.50]-- -NAKivistö, 2016 1 All studiesAll studies 0.97[0.38; 2.50]-- -NAKivistö, 2016 10.210.01.0

Publication bias and p-hacking diagnosis

funnel plot

Funnel plot not drawn. Less than 3 points.

Asymetry test p-value = NaN (by Egger's regression)

not enought points

p values plot

Funnel plot not drawn. Less than 3 points.

Sub-groups analysis using all included studies

excluded

Sub-groupsTE95% CIn casesn exposedkI2ROB type of controls unexposed controls (disease free or unspecified)unexposed controls (disease free or unspecified) 0.97[0.38; 2.50]2,560- -NAKivistö, 2016 10.510.01.0