| id | Study | Lib. in paper | Exposition period | Study type |
Control type |
Tags | OR 95%CI | x1/n1 x0/n0 | no cases | no exposed | ROB | Ref. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| S18445 R78340 |
Lee (Controls exposed to SSRI), 2025 | Large for gestational age (birth weight >2 standard deviations above the mean for gestational age) | during pregnancy (anytime or not specified) | retrospective cohort (claims database) | exposed to other treatment, sick excluded | Adjustment: No Monotherapy: TCA only |
0.92 [0.44;1.92] C excluded (control group) |
10/613 26/1,465 | 36 | 613 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S18410 R77741 |
Lee (Controls unexposed, general pop), 2025 | Large for gestational age (birth weight >2 standard deviations above the mean for gestational age) | during pregnancy (anytime or not specified) | retrospective cohort (claims database) | unexposed (general population or NOS) | Adjustment: Yes Monotherapy: TCA only | 0.55 [0.29;1.03] | 10/613 9,744/463,440 | 9,754 | 613 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S10933 R40666 |
Reis (Controls exposed to SSRIs), 2010 | Large for gestational age (>2 S.D. from expected weight) | 2nd and/or 3rd trimester | population based cohort retrospective | exposed to other treatment, sick excluded | Adjustment: No Monotherapy: TCA only |
1.24 [0.92;1.66] C excluded (control group) |
58/784 292/4,809 | 350 | 784 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| S10934 R40669 |
Reis (Controls unexposed, NOS), 2010 | Large for gestational age (>2 S.D. from expected weight) | 2nd and/or 3rd trimester | population based cohort retrospective | unexposed (general population or NOS) | Adjustment: Yes Monotherapy: TCA only | 1.12 [0.85;1.48] | 58/784 68,814/1,062,190 | 68,872 | 784 |
|
ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Total | 2 studies | 0.83 [0.42;1.66] | 78,626 | 1,397 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1: Controls unexposed, general pop; 2: Controls unexposed, NOS;
Funnel plot not drawn. Less than 3 points.
Asymetry test p-value = NaN (by Egger's regression)
not enought points
Funnel plot not drawn. Less than 3 points.
excluded 10933, 18445