id | Study | Lib. in paper | Exposition period | Study type |
Control type |
Tags | OR 95%CI | x1/n1 x0/n0 | no cases | no exposed | ROB | Ref. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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S7510 R25077 |
Huber-Mollema (Carbamazepine), 2019 | ADHD total (Social Emotional Questionnaire) (Completed by mothers) Clinical cutoff | throughout pregnancy | prospective cohort | exposed to other treatment, sick | Adjustment: No | 0.47 [0.05;4.16] C | 1/36 5/87 | 6 | 36 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S5542 R21099 |
Cohen (Carbamazepine), 2013 | Children with either ADHD inattentive OR combined types > 1 SD (from the Attention Problems and Hyperactivity scales of the BASC) (Parent) | during pregnancy (anytime or not specified) | prospective cohort | exposed to other treatment, sick | Adjustment: No | 1.61 [0.56;4.69] C | 9/52 7/61 | 16 | 52 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S6356 R17305 |
Veiby (Carbamazepine) (Controls exposed to Lamotrigine, sick) b, 2013 | ADHD symptoms ≥ 2SD (at 36 months) (Specific checklist) (Parent-reported) | during pregnancy (anytime or not specified) | prospective cohort | exposed to other treatment, sick excluded | Adjustment: No |
0.94 [0.15;6.00] C excluded (control group) |
2/31 3/44 | 5 | 31 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S6354 R17281 |
Veiby (Carbamazepine) (Controls unexposed, disease free) b, 2013 | ADHD symptoms ≥ 2SD (at 36 months) (Specific checklist) (Parent-reported) | during pregnancy (anytime or not specified) | prospective cohort | unexposed, disease free excluded | Adjustment: No |
2.00 [0.50;8.60] excluded (control group) |
2/31 1,743/43,571 | 1,745 | 31 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S6355 R17293 |
Veiby (Carbamazepine) (Controls unexposed, sick) b, 2013 | ADHD symptoms ≥ 2SD (at 36 months) (Specific checklist) (Parent-reported) | during pregnancy (anytime or not specified) | prospective cohort | unexposed, sick | Adjustment: No | 2.59 [0.45;14.78] C | 2/31 4/154 | 6 | 31 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S5831 R20621 |
Viinikainen (Carbamazepine) b, 2006 | Conners' Teacher Rating Scale Global Index scores >1 SD | throughout pregnancy | prospective cohort | unexposed, sick | Adjustment: No | 0.15 [0.01;3.50] C | 0/12 2/11 | 2 | 12 |
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ref | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Total | 4 studies | 1.23 [0.49;3.05] | 30 | 131 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
x1: number of endpoints among exposed, n1: number of exposed; x0: number of endpoints among non exposed, n0: number of non exposed; C: calculated odds ratio from numbers of events and effectives |
1: Carbamazepine; 2: Carbamazepine; 3: Carbamazepine) (Controls unexposed, sick) ; 4: Carbamazepine) ;
Asymetry test p-value = NaN (by Egger's regression)
not enought points
excluded 6356, 6354